CureFIP™ GS-441524 + B12 Injectable 30mg/ml
Standard FIP Treatment With Integrated Cobalamin Support for Adult Cats
What This Product Is
CureFIP™ GS-441524 + B12 30mg/ml is the B12-enhanced version of our most widely used injectable formulation. It delivers GS-441524 at the standard treatment concentration for adult cats (2.5–5 kg) with the addition of cyanocobalamin (Vitamin B12) at 50mcg/ml — addressing the secondary systemic complications that frequently accompany FIP in the standard adult cat weight range.
The antiviral component is identical to the standard 30mg/ml formulation in every respect. B12 addition does not alter GS-441524 concentration, dosing calculation, or mechanism of action. It integrates nutritional support into the existing daily injection, removing the need for a separate B12 administration during the treatment period.
The Clinical Case for B12 in Standard-Weight FIP Cats
The 30mg/ml formulation serves adult cats in the 2.5–5 kg range — the most common FIP presentation weight. Within this cohort, a significant proportion arrive at treatment with secondary systemic compromise that extends beyond the primary viral pathology. These are not edge cases. Anaemia, appetite suppression, and immune compromise are common FIP presentations across all weight ranges — not exclusive to small or severely ill cats.
GS-441524 addresses the root cause — viral replication. It does not immediately reverse the systemic damage the virus has already produced. Cobalamin at 50mcg/ml works in parallel with the antiviral mechanism across four physiological pathways:
Red blood cell production: Cobalamin is an essential cofactor in erythropoiesis. FIP-associated anaemia responds to B12 supplementation alongside the removal of the underlying viral inflammatory driver. Supporting haematopoiesis from the first day of treatment accelerates the cat's return to normal haematological parameters.
Neurological recovery: B12-dependent myelin sheath maintenance is relevant not only in neurological FIP presentations but in any cat whose systemic illness has produced peripheral neurological effects — including the generalised weakness and proprioceptive deficits seen in severe wet FIP cases.
Appetite restoration: Cobalamin's role in appetite pathway activation is well documented in cats. Many owners report observable appetite improvement within the first 2–3 days of B12 administration — earlier than the typical GS-441524 antiviral response window of 5–7 days. This early appetite signal provides owners with a tangible early indicator that treatment is being tolerated.
Immune support: Cobalamin is a cofactor in lymphocyte proliferation and immune regulatory processes. FIP produces significant immune dysregulation. B12 supplementation supports immune system recovery alongside viral clearance.
Indicated Cases
This formulation is most appropriate for:
- Adult cats 2.5–5 kg with FIP presenting alongside anaemia (confirmed by haematology or suspected clinically)
- Wet FIP cases with concurrent lethargy and appetite suppression disproportionate to effusion severity
- Dry FIP cases with systemic involvement and immune compromise
- Cases where owner or veterinarian wishes to consolidate daily antiviral injection with B12 supplementation
- Cats on concurrent medications that may affect appetite or GI absorption
This Formulation Is Not the First Choice For
- Cats requiring therapeutic-dose B12 at intervals other than once daily — maintain a separate B12 protocol as directed by your veterinarian
- Cats outside the 2.5–5 kg weight range — select the appropriate concentration for your cat's weight
- Cats with no secondary systemic complications — the standard 30mg/ml formulation is sufficient
Concentration Selection Guide
| Concentration | Primary Indication |
|---|---|
| 20mg/ml + B12 | Cats under 2.5 kg with systemic complications |
| 30mg/ml + B12 (this product) | Cats 2.5–5 kg with anaemia, neurological symptoms, or appetite loss |
| 40mg/ml + B12 | Cats over 5 kg with high-dose protocol and systemic complications |
| 30mg/ml | Cats 2.5–5 kg · Standard antiviral · No secondary complications |
Administration
Administer subcutaneously once daily. Dose is calculated in mg of GS-441524 per kg of body weight. B12 addition does not alter the dose calculation. Standard treatment duration is 84 consecutive days. Use the dosing calculator to determine the correct volume for your cat's current weight.
GS-441524 Antiviral with Vitamin B12 | 30mg/ml
Chemical Formula: C12 H13 N5 O4
Concentration: 30mg/ml
Quantity: 1 vial
Purity: 99.4%
pH: 2.2
Formulation: 5% ethanol, 30% propylene glycol, 45% PEG 400, 20% water.
Shelf Life: 1 Year, Vials must be stored at ROOM TEMPERATURE. Do not store the vials in the freezer or the cooler or temperature below 8 degree celsius or 46 degree Fahrenheit, which may result in precipitation of API or crystallization of API.
Reviews
After two days our Rudy Tooty sphynx cat started to eat again. His belly began to lessen on day 5 (he has wet FIP). No draining was necessary and by day ten no belly at all.
We are on day 49 and have him back in personality,mischief and strength. We will continue treatments for the recommended time period but plan to switch to pills . Since he's regained his strength it is diffulct to inject him.
We also now do two injection sites each day due to the volume he needs with his body weight back.
This product is amazing and I truly recommend it for any of your kitties that have FIP. I already see a significant difference in my kitten. He’s doing so much better after just 5days of taking these injections! Will be getting more!
I have used this product on 2 of my cats. I noticed immediate improvement with my one cat and slower improvement on my 2nd cat Both are doing well and have gained weight. Yaaay
Cat had wet FIP. Improvement after 3 days, much better after a week and then switched to pills. Now 3 weeks out, energy has returned!
This treatment is real cats life saver . Thank you so much!