CureFIP™ GS-441524 Injectable 20mg/ml
Precision Dosing Formulation for Small Cats and Kittens
What This Product Is
CureFIP™ GS-441524 20mg/ml is the lowest-concentration injectable in our range. It contains the same active antiviral compound — GS-441524 — as our 30mg/ml and 40mg/ml formulations. The total dose of GS-441524 delivered per treatment (measured in mg per kg of body weight) is identical across all three concentrations. Concentration does not determine efficacy. It determines injection volume — and injection volume determines dosing accuracy.
Why Concentration Matters for Small Cats
FIP treatment dosing is calculated in mg of GS-441524 per kg of body weight. In cats weighing under 2.5 kg, the required dose per injection is small in absolute terms. When that small dose is drawn from a high-concentration formulation, the resulting injection volume becomes extremely small — often below the reliable measurement threshold of standard syringes.
A measurement error of 0.05ml in a 0.1ml injection represents a 50% dosing error. In FIP treatment, consistent and accurate dosing across all 84 days of the protocol directly influences treatment outcome. Underdosing extends the time to remission and increases resistance risk. Overdosing creates unnecessary burden on a small cat's physiology.
The 20mg/ml format resolves this by producing a clinically manageable injection volume for cats in the under-2.5 kg weight range, where dosing precision matters most.
Indicated Cases
This formulation is appropriate for:
- Adult cats weighing under 2.5 kg
- Kittens diagnosed with FIP at any stage
- Cats that have lost significant weight during illness and now fall below 2.5 kg
- Cases where the attending veterinarian has specified low-concentration formulation for precision dosing
This Formulation Is Not the First Choice For
- Cats weighing 2.5 kg or above — the 30mg/ml formulation is more appropriate
- Cases requiring high-dose induction protocols — the 40mg/ml formulation is indicated
- Cases presenting with anaemia, neurological involvement, or significant appetite loss — consider the CureFIP™ GS-441524 + B12 20mg/ml formulation, which integrates cobalamin support alongside antiviral treatment
Clinical Background
GS-441524 is a nucleoside analogue that functions as an RNA-dependent RNA polymerase (RdRp) inhibitor. Following cellular uptake and phosphorylation to its active triphosphate form, it is incorporated into nascent viral RNA chains, causing delayed chain termination and halting feline coronavirus (FCoV/FIPV) replication. The compound was identified as an effective FIP treatment in landmark research published in Nature in 2019 (Pedersen et al.) and has since been evaluated in multiple prospective and retrospective clinical studies across thousands of cases globally.
The 20mg/ml concentration contains the same pharmaceutical-grade GS-441524 as all CureFIP™ injectable formulations. Concentration variation is a manufacturing and clinical precision decision, not a quality distinction.
Concentration Selection Guide
| Concentration | Primary Indication |
|---|---|
| 20mg/ml (this product) | Cats under 2.5 kg · Kittens · Precision low-volume dosing |
| 30mg/ml | Cats 2.5–5 kg · Standard FIP cases · First-line treatment |
| 40mg/ml | Cats over 5 kg · High-dose protocols · Resistance · Relapse |
| 20mg/ml + B12 | Cats under 2.5 kg with anaemia, neurological symptoms, or appetite loss |
Administration
Administer subcutaneously once daily. Dose is calculated in mg of GS-441524 per kg of body weight. The standard treatment duration is 84 days of consecutive daily dosing without interruption. Do not adjust dose without veterinary guidance. Use the dosing calculator to determine the correct volume for your cat's current weight.
Treatment response is typically observed within the first 7 days — appetite improvement, reduction in fever, and increased activity are the earliest indicators. If no response is observed within 7 days, contact our clinical support team before discontinuing treatment.
Quality and Sourcing
CureFIP™ injectables are manufactured to pharmaceutical-grade standards with documented API sourcing, concentration verification, and stability testing. Each batch is tested for GS-441524 concentration accuracy before release. We provide full transparency on formulation specifications — contact our team for batch documentation if required for veterinary records.
GS-441524 Antiviral Injectables | 20mg/ml
Chemical Formula: C12 H13 N5 O4
Concentration: 20mg/ml
B12 Concentration: 50mcg/ml
Quantity: 1 vial
Purity: 99.4%
pH: 2.2Formulation: 5% ethanol, 30% propylene glycol, 45% PEG 400, 20% water.
Shelf Life: 1 Year, Vials must be stored at ROOM TEMPERATURE. Do not store the vials in the freezer or the cooler or temperature below 8 degree celsius or 46 degree Fahrenheit, which may result in precipitation of API or crystallization of API.
Reviews
I was devastated when i first heard it from my local vet. It was really hard for us to digest for this but thankfully I stumble across one of their page on Facebook where i get to discovered about how GS can treat FIP. I did not waste anytime longer and immediately consult with CUREFIP regarding cacao's condition. He started to show some positive improvement within a week! much more playful and eats a lot too! Now he's on 40th day and healthy as ever. The result even came back as negative!
My cat is my heart. When it was found through bloodwork that she had fip , I was devastdated. I had wondered why her eyes looked strange and unfocused. She has been getting injections for 2 weeks an is showing definite improvement. She has neurological problems. Her walking was impacted and she could barely stand up. She was lethargic. She is now able to run although so isn't 100% yet, but I have confidence that she will recover with further treatment as all signs point to improvement.
I started May 17th with the injection and he responded within 48 hours! Bear was very sick, he could not walk or eat/drink on his own. By day 3 he was up slowly walking to his food and water bowl! We are coming up on week 3 and you would never know he was so sick. He was diagnosed with neuro fip and had a very very little chance of recovery. I'm so happy I found out about CureFIP. Please keepoing praying for Bear we still have a ways to go, but he is responding so well!
I ordered 2 vials of the 20ml for my cat per my vets suggestion after diagnosis. He is doing so much better after 30 days. All symptoms are gone and he is eating, playful and cleaning himself again. Thank you! The med was affordable compared to others, and my cat is back to feeling well.
My only 4 months old kitten got FIP. The vet told me that it was incurable and recommended to put him down. This medicine is our last hope. As soon as we start the treatment, he gets better! Hope that he could be a survivor of FIP like other kittens here.